The 3 Reasons GTA 5 Breaks
After years of modding and troubleshooting you'll likely come to the irrefutable conclusion that there are 3 reasons that summarize just about every single cause for modded game crashes, infinite loads, texture loss, or FPS drops. Of course your hardware must meet or exceed requirements. Here we go.
Reason 1 - Changes
You the gamer, or Rockstar the developer, made changes to your GTA 5 game. This could be a game patch, the installation of an addon, replace, script dll, asi mod, a meta or xml file edit, an OIV installation, or changes to your hardware or Windows software. Changes could also be that a file, for example your save game file, somehow got corrupted. Just modding your game is the principal reason games crash or get stuck with an infinite loading screens.
Any change, particularly the most recent one (the last one), can break the delicate equilibrium between vanilla and modded games, regardless of whether the change was done as per the instructions. Correctly or incorrectly implemented, changing the game or its environment opens the door for problems.
Step by step is the best advice, so keep track of those last changes, even the apparently innocuous ones. If you can revert the changes you undo the damage.
Reason 2 -Setup and Configuration
Maybe your game was never going to run GTA5 modded in the first place. Perhaps you didn't install all the essential files such as ScriptHook5, or the heap and packfile adjusters. Maybe you tried but didn't install them properly. Finally, you might not have the proper hardware and software, or all of the above.
The proper modded game setup, on hardware exceeding recommended vanilla requirements, is an absolute must to ensure a solid modding foundation.
Reason 3 -Overdoing Modding
GTA 5 was not developed by Rockstar to be modded. Thankfully it can. However, you shouldn't push the game beyond its modding limits and/ or beyond the limits of your hardware. One of the most common causes of crashes is simply you have too many mods installed - mods that eat up memory and mods that can conflict with each other, particularly script and graphic enhancement mods.
Installing 100s of mods and scripts and tools and visual mods, even on the most powerful hardware, even tweaking gameconfig.xml and installing all the pool managers and resource adjusting mods, will in no way enable you to abuse the game. At some point it will scream, Enuf! Go slowly and act judiciously. One method is to enable or disable mods selectively by simply renaming them before a session.
TO LEARN MORE: Why GTA 5 Crashes for Dummies